Aarthi Gopinathan

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

Kenneth P. Olive, Michael A. Jacobetz, Christian J. Davidson et al. · Science · 2009 · 3.1K citations · Full text

Tumor Biology, Oncology, Pancreatic Cancer +12

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Gina M. DeNicola, Florian A. Karreth, Timothy J. Humpton et al. · Nature · 2011 · 2.2K citations · Full text

Oncogenic Agent, Oncogene-induced Nrf2 Transcription, Reactive Oxygen Specie +5

Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein–α

Matthew Kraman, Paul Bambrough, James N. Arnold et al. · Science · 2010 · 1.1K citations

Fap-expressing Cells, Immunology, Immune Regulation +23

KrasG12D and Smad4/Dpc4 Haploinsufficiency Cooperate to Induce Mucinous Cystic Neoplasms and Invasive Adenocarcinoma of the Pancreas

Kamel Izeradjene, Chelsea Combs, Melissa Best et al. · Cancer Cell · 2007 · 370 citations · Full text

Pancreatic Cancer, Medicine, Invasive Adenocarcinoma +8

CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response

Daniele Biasci, Martin Smoragiewicz, Claire M. Connell et al. · Proceedings of the National Academy of Sciences · 2020 · 241 citations · Full text