René C. van Schaik

Avoiding singularities and numerical instabilities in free energy calculations based on molecular simulations

Thomas C. Beutler, Alan E. Mark, René C. van Schaik et al. · Chemical Physics Letters · 1994 · 1.1K citations

Engineering, Physics, Natural Sciences +11

A Structure Refinement Method Based on Molecular Dynamics in Four Spatial Dimensions

René C. van Schaik, Herman J. C. Berendsen, Andrew E. Torda et al. · Journal of Molecular Biology · 1993 · 86 citations

Four Spatial Dimensions, Engineering, Molecular Biology +11

Internal Mobility of the Basic Pancreatic Trypsin Inhibitor in Solution: A Comparison of NMR Spin Relaxation Measurements and Molecular Dynamics Simulations

Paul E. Smith, René C. van Schaik, Thomas Szyperski et al. · Journal of Molecular Biology · 1995 · 71 citations

Biophysical Modeling, Biochemistry, Protein Folding +7

The High-resolution Structure of the Histidine-containing Phosphocarrier Protein HPr from Escherichia coli Determined by Restrained Molecular Dynamics from Nuclear Magnetic Resonance Nuclear Overhauser Effect Data

Nico A. J. van Nuland, Ilona W. Hangyi, René C. van Schaik et al. · Journal of Molecular Biology · 1994 · 65 citations

Biochemistry, Structural Bioinformatics, Natural Sciences +7

Interpretation of ANOVA models for microarray data using PCA

Jorn R. de Haan, Ron Wehrens, Susanne Bauerschmidt et al. · Bioinformatics · 2006 · 65 citations · Full text