Jie Shi

USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy

Wenjun Xiong, Xueliang Gao, Tiantian Zhang et al. · Nature Communications · 2022 · 138 citations · Full text

USP8-governed GPX4 homeostasis orchestrates ferroptosis and cancer immunotherapy

H. Li, Yishuang Sun, Yingmeng Yao et al. · Proceedings of the National Academy of Sciences · 2024 · 100 citations · Full text

ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy

Xiangling Xiao, Jie Shi, Chuan He et al. · Nature Communications · 2023 · 73 citations · Full text

UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity

Chuan He, Xixin Xing, Hsin-Yi Chen et al. · Molecular Cell · 2024 · 46 citations · Full text

The epitranscriptional factor PCIF1 orchestrates CD8+ T cell ferroptosis and activation to control antitumor immunity

Bolin Xiang, Meiling Zhang, Kai Li et al. · Nature Immunology · 2025 · 12 citations