Wesley L. Cai

Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection

Jin Wei, Mia Madel Alfajaro, Peter C. DeWeirdt et al. · Cell · 2020 · 572 citations · Full text

Sars-cov-2 Infection, Pathogenesis, Virology +8

KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements

Shang‐Min Zhang, Wesley L. Cai, Xiaoni Liu et al. · Nature · 2021 · 245 citations · Full text

Immunogenetics, Immune Evasion, Adaptive Immune System +6

An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting

Jian Cao, Lizhen Wu, Shang‐Min Zhang et al. · Nucleic Acids Research · 2016 · 226 citations · Full text

Potent BRD4 inhibitor suppresses cancer cell-macrophage interaction

Mingzhu Yin, Ying Guo, Rui Hu et al. · Nature Communications · 2020 · 183 citations · Full text

Potent Brd4 Inhibitor, Immunology, Small Molecule Inhibitor +16

KDM5 histone demethylases repress immune response via suppression of STING

Lizhen Wu, Jian Cao, Wesley L. Cai et al. · PLoS Biology · 2018 · 160 citations · Full text

Epigenetic Change, Immunology, Immunoediting +20