Hamed W. El-Shafey

New benzothiazole hybrids as potential VEGFR-2 inhibitors: design, synthesis, anticancer evaluation, and <i>in silico</i> study

Mohammad M. Al‐Sanea, Abdelrahman Hamdi, Ahmed A. B. Mohamed et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2023 · 44 citations · Full text

Synthetic approaches, anticancer potential, HSP90 inhibition, multitarget evaluation, molecular modeling and apoptosis mechanistic study of thioquinazolinone skeleton: Promising antibreast cancer agent

Hamed W. El-Shafey, Rania M. Gomaa, Shahenda M. El‐Messery et al. · Bioorganic Chemistry · 2020 · 38 citations

Thioquinazolinone Skeleton, Medicine, Synthetic Approaches +8

Design, synthesis, antitumor, and VEGFR-2 inhibition activities of novel 4-anilino-2-vinyl-quinazolines: Molecular modeling studies

Abdelrahman Hamdi, Hamed W. El-Shafey, Dina I. A. Othman et al. · Bioorganic Chemistry · 2022 · 28 citations

Medicinal Chemistry, Engineering, Medicine +10

Development of new thiazolidine-2,4-dione hybrids as aldose reductase inhibitors endowed with antihyperglycaemic activity: design, synthesis, biological investigations, and <i>in silico</i> insights

Abdelrahman Hamdi, Muhammad Yaseen, Wafaa A Ewes et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2023 · 25 citations · Full text

Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting

Hamed W. El-Shafey, Rania M. Gomaa, Shahenda M. El‐Messery et al. · Bioorganic & Medicinal Chemistry Letters · 2020 · 21 citations · Full text

Drug Target, Breast Oncology, Drug Targeting +10