Natalie J. Wegner

Comparative Functional Analysis of <i>DPYD</i> Variants of Potential Clinical Relevance to Dihydropyrimidine Dehydrogenase Activity

Steven M. Offer, Croix C. Fossum, Natalie J. Wegner et al. · Cancer Research · 2014 · 172 citations · Full text

Molecular Pharmacology, Aldehyde Dehydrogenase, Comparative Functional Analysis +15

Phenotypic Profiling of <i>DPYD</i> Variations Relevant to 5-Fluorouracil Sensitivity Using Real-time Cellular Analysis and <i>In Vitro</i> Measurement of Enzyme Activity

Steven M. Offer, Natalie J. Wegner, Croix C. Fossum et al. · Cancer Research · 2013 · 123 citations · Full text

Chemoprevention Strategy, Molecular Biology, Pathology +22

A DPYD Variant (Y186C) in Individuals of African Ancestry Is Associated With Reduced DPD Enzyme Activity

Steven M. Offer, A M Lee, Lori K. Mattison et al. · Clinical Pharmacology & Therapeutics · 2013 · 101 citations · Full text

microRNAs miR-27a and miR-27b Directly Regulate Liver Dihydropyrimidine Dehydrogenase Expression through Two Conserved Binding Sites

Steven M. Offer, Gabriel L. Butterfield, Calvin R. Jerde et al. · Molecular Cancer Therapeutics · 2014 · 87 citations · Full text