Judith Günther

Utilising Structural Knowledge in Drug Design Strategies: Applications Using Relibase

Judith Günther, Andreas Bergner, Manfred Hendlich et al. · Journal of Molecular Biology · 2003 · 110 citations

Drug Repositioning, Structural Knowledge, Drug Target +10

Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design

Fredrik Rahm, Jenny Viklund, L. Tresaugues et al. · Journal of Medicinal Chemistry · 2018 · 33 citations · Full text

Discovery of a hidden transient state in all bromodomain families

Lluı́s Raich, Katharina Meier, Judith Günther et al. · Proceedings of the National Academy of Sciences · 2021 · 32 citations · Full text

Design and synthesis of macrocyclic inhibitors of phosphatase Cdc25B

Stefan Bäurle, Thorsten Blume, Judith Günther et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 25 citations · Full text

Medicinal Chemistry, Medicine, Anti-cancer Agent +5

Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent, and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels in Vivo

Lars Wortmann, B. Lindenthal, Peter Muhn et al. · Journal of Medicinal Chemistry · 2019 · 22 citations · Full text

Sex Hormones, Gynecology, Pharmacotherapy +17