Nels Thorsteinson

Antibody modeling assessment

Juan C. Almagro, Mary Pat Beavers, Francisco G. Hernandez-Guzman et al. · Proteins Structure Function and Bioinformatics · 2011 · 129 citations

Immunoglobulin Structure, Biomolecular Structure Prediction, Immunology +18

Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries

Michael R. Dyson, Edward W. Masters, Deividas Pazeraitis et al. · mAbs · 2020 · 66 citations · Full text

Immunocytochemical Technique, Engineering, Mammalian Display Libraries +22

Identifying biophysical assays and <i>in silico</i> properties that enrich for slow clearance in clinical-stage therapeutic antibodies

Boris Grinshpun, Nels Thorsteinson, Joao NS Pereira et al. · mAbs · 2021 · 46 citations · Full text

An Updated Steroid Benchmark Set and Its Application in the Discovery of Novel Nanomolar Ligands of Sex Hormone-Binding Globulin

Artem Cherkasov, Fuqiang Ban, Osvaldo A. Santos‐Filho et al. · Journal of Medicinal Chemistry · 2008 · 42 citations · Full text

Structure-based charge calculations for predicting isoelectric point, viscosity, clearance, and profiling antibody therapeutics

Nels Thorsteinson, John R. Gunn, Kenneth Kelly et al. · mAbs · 2021 · 42 citations · Full text

Immunocytochemical Technique, Engineering, Immunology +22