Robert E. Drolet

A highly reproducible rotenone model of Parkinson's disease

Jason R. Cannon, Vı́ctor Tapias, Hye Mee Na et al. · Neurobiology of Disease · 2009 · 793 citations · Full text

Life Sciences, Neurobiology, Neuroscience +10

Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology

Robert E. Drolet, Jason R. Cannon, Laura Montero et al. · Neurobiology of Disease · 2009 · 253 citations · Full text

Life Sciences, Neuroscience, Toxicology +13

Internalized Tau Oligomers Cause Neurodegeneration by Inducing Accumulation of Pathogenic Tau in Human Neurons Derived from Induced Pluripotent Stem Cells

Marija Usenovic, Shahriar Niroomand, Robert E. Drolet et al. · Journal of Neuroscience · 2015 · 252 citations · Full text

Life Sciences, Neurology, Neuroscience +17

TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation

Sarah Jinn, Robert E. Drolet, Paige E. Cramer et al. · Proceedings of the National Academy of Sciences · 2017 · 251 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity

Jack D. Scott, Duane E. DeMong, Thomas J. Greshock et al. · Journal of Medicinal Chemistry · 2017 · 148 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16