Markus Kügler

A recombinant trispecific single‐chain Fv derivative directed against CD123 and CD33 mediates effective elimination of acute myeloid leukaemia cells by dual targeting

Markus Kügler, Christoph Stein, Christian Kellner et al. · British Journal of Haematology · 2010 · 128 citations · Full text

Hematological Malignancy, Malignant Blood Disorder, Immunology +14

Novel conjugates of single‐chain Fv antibody fragments specific for stem cell antigen CD123 mediate potent death of acute myeloid leukaemia cells

Christoph Stein, Christian Kellner, Markus Kügler et al. · British Journal of Haematology · 2010 · 71 citations · Full text

Cancer Immunosurveillance, Medicine, Spleen Rna +13

A single-chain triplebody with specificity for CD19 and CD33 mediates effective lysis of mixed lineage leukemia cells by dual targeting

Ingo Schubert, Christian Kellner, Christoph Stein et al. · mAbs · 2011 · 56 citations · Full text

Stabilization and humanization of a single-chain Fv antibody fragment specific for human lymphocyte antigen CD19 by designed point mutations and CDR-grafting onto a human framework

Markus Kügler, Christoph Stein, Michael Schwenkert et al. · Protein Engineering Design and Selection · 2009 · 55 citations · Full text

Immunology, Immunodominance, Molecular Biology +21

A recombinant triplebody with specificity for CD19 and HLA-DR mediates 
preferential binding to antigen double-positive cells by dual-targeting

Ingo Schubert, Christian Kellner, Christoph Stein et al. · mAbs · 2012 · 27 citations · Full text

Histocompatibility, Immune Regulation, Immunology +26