Mal Irvine

The molecular and functional landscape of resistance to immune checkpoint blockade in melanoma

Su Yin Lim, Elena Shklovskaya, Jenny Lee et al. · Nature Communications · 2023 · 116 citations · Full text

Oncogenic PI3K/AKT promotes the step-wise evolution of combination BRAF/MEK inhibitor resistance in melanoma

Mal Irvine, Ashleigh Stewart, Bernadette Pedersen et al. · Oncogenesis · 2018 · 103 citations · Full text

Step-wise Evolution, Skin Cancer, Oncogenic Pi3k/akt +14

Preexisting MEK1P124 Mutations Diminish Response to BRAF Inhibitors in Metastatic Melanoma Patients

Matteo S. Carlino, Carina Fung, Hamideh Shahheydari et al. · Clinical Cancer Research · 2014 · 70 citations · Full text

IGFBP7 Is Not Required for B-RAF-Induced Melanocyte Senescence

Lyndee L. Scurr, Gulietta M. Pupo, Therese M. Becker et al. · Cell · 2010 · 60 citations · Full text

Cell Biology, Cellular Senescence, B-raf-induced Melanocyte Senescence

Predicting functional significance of cancer-associated p16INK4a mutations in CDKN2A

Heather McKenzie, Carina Fung, Therese M. Becker et al. · Human Mutation · 2010 · 37 citations · Full text