Simonetta M. Leto

Effective drug combinations in breast, colon and pancreatic cancer cells

Patricia Jaaks, Elizabeth A. Coker, Daniël J. Vis et al. · Nature · 2022 · 433 citations · Full text

HER2 Activating Mutations Are Targets for Colorectal Cancer Treatment

Shyam M. Kavuri, Naveen Jain, Francesco Galimi et al. · Cancer Discovery · 2015 · 286 citations · Full text

IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies

Eugenia R. Zanella, Francesco Galimi, Francesco Sassi et al. · Science Translational Medicine · 2015 · 112 citations · Full text

Tumor Biology, Marginal Response, Stable Disease +14

Sustained Inhibition of HER3 and EGFR Is Necessary to Induce Regression of <i>HER2</i> -Amplified Gastrointestinal Carcinomas

Simonetta M. Leto, Francesco Sassi, Irene Catalano et al. · Clinical Cancer Research · 2015 · 101 citations

Synthetic Lethal Interaction with BCL-XL Blockade Deepens Response to Cetuximab in Patient-Derived Models of Metastatic Colorectal Cancer

Simonetta M. Leto, Martina Ferri, Francesco Sassi et al. · Clinical Cancer Research · 2023 · 44 citations · Full text