Nu <scp>MA</scp> assemblies organize microtubule asters to establish spindle bipolarity in acentrosomal human cells

Takumi Chinen, Shohei Yamamoto, Yutaka Takeda, +5

The EMBO Journal

Cell DivisionMedicineNatural SciencesMolecular BiologyCellular Biology +10

Synthesis and Structure–Activity Relationship Study of Antimicrotubule Agents Phenylahistin Derivatives with a Didehydropiperazine-2,5-dione Structure

Yuri Yamazaki, Koji Tanaka, Benjamin Nicholson, +19

Journal of Medicinal Chemistry

Pharmaceutical ScienceOrganic ChemistryMicrotubule DepolymerizationPharmaceutical ChemistryMedicinal Chemistry +14

Stress-dependent cell stiffening by tardigrade tolerance proteins that reversibly form a filamentous network and gel

Akihiro Tanaka, Tomomi Nakano, Kento Watanabe, +12

PLoS Biology

Inhibition of Microtubule Assembly by a Complex of Actin and Antitumor Macrolide Aplyronine A

Masaki Kita, Yuichiro Hirayama, Kozo Yoneda, +6

Journal of the American Chemical Society

MedicineNatural SciencesMacromolecular MachineMolecular BiologyMicrotubule Inhibitors +12

The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle

Takumi Chinen, Peng Liu, Shuya Shioda, +11

Nature Communications

MOZART1 and γ-tubulin complex receptors are both required to turn γ-TuSC into an active microtubule nucleation template

Tien-chen Lin, Annett Neuner, Dirk Flemming, +4

The Journal of Cell Biology

Syntheses and Biological Evaluation of Irciniastatin A and the C1−C2 Alkyne Analogue

Tsubasa Watanabe, Takamichi Imaizumi, Takumi Chinen, +5

Organic Letters

Robust classification of cell cycle phase and biological feature extraction by image-based deep learning

Yukiko Nagao, Mika Sakamoto, Takumi Chinen, +2

Molecular Biology of the Cell

Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly

Takumi Chinen, Kaho Yamazaki, Kaho Hashimoto, +8

The Journal of Cell Biology

Materials ScienceSpintronicsChromatinBipolar Spindle AssemblyBipolar Spindle Formation +13

Synthesis and structure–activity relationships of benzophenone-bearing diketopiperazine-type anti-microtubule agents

Yuri Yamazaki, Makiko Sumikura, Yurika Masuda, +11

Bioorganic & Medicinal Chemistry

HeterocyclicMedicineOrganic ChemistryStructure–activity RelationshipsChemistry +3