Jef K. De Brabander

A Small Molecule Smac Mimic Potentiates TRAIL- and TNFα-Mediated Cell Death

Li Lin, Ranny Mathew Thomas, Hidetaka Suzuki et al. · Science · 2004 · 658 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

Cholesterol and 25-Hydroxycholesterol Inhibit Activation of SREBPs by Different Mechanisms, Both Involving SCAP and Insigs

Christopher M. Adams, Julian Reitz, Jef K. De Brabander et al. · Journal of Biological Chemistry · 2004 · 454 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Discovery of a Proneurogenic, Neuroprotective Chemical

Andrew A. Pieper, Shanhai Xie, Emanuela Capota et al. · Cell · 2010 · 342 citations · Full text

Medicine, Medicinal Chemistry, Neuroscience +9

Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection

Feiran Lu, Qiren Liang, Lina Abi-Mosleh et al. · eLife · 2015 · 342 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma

Yufeng Shi, Sang Kyun Lim, Qiren Liang et al. · Nature · 2019 · 330 citations · Full text

Medicine, Oncology, Pharmacology +11