Zhen-Quan Liu

Discovery of Small Molecules for Up-Regulating the Translation of Antiamyloidogenic Secretase, a Disintegrin and Metalloproteinase 10 (ADAM10), by Binding to the G-Quadruplex-Forming Sequence in the 5′ Untranslated Region (UTR) of Its mRNA

Jie Dai, Zhen-Quan Liu, Xiaoqin Wang et al. · Journal of Medicinal Chemistry · 2015 · 53 citations

Protein Secretion, Molecular Biology, Peptide Science +19

Synthesis and evaluation of 1,2,3,4-tetrahydro-1-acridone analogues as potential dual inhibitors for amyloid-beta and tau aggregation

Peng Lv, Chunli Xia, Ning Wang et al. · Bioorganic & Medicinal Chemistry · 2018 · 33 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Pharmaceutical Chemistry +8

Design, synthesis and evaluation of 2-arylethenyl- N -methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment

Chunli Xia, Ning Wang, Qian-Liang Guo et al. · European Journal of Medicinal Chemistry · 2017 · 26 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Disease Treatment +10

Facile syntheses of disubstituted bis(vinylquinolinium)benzene derivatives as G-quadruplex DNA binders

Zhen-Quan Liu, Shitian Zhuo, Jia‐Heng Tan et al. · Tetrahedron · 2013 · 23 citations

Bioorganic Chemistry, Derivatives, Natural Sciences +6