Michael D. Crowther

Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1

Michael D. Crowther, Garry Dolton, Mateusz Legut et al. · Nature Immunology · 2020 · 263 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination

Sophie V. Pageon, Thibault Tabarin, Yui Yamamoto et al. · Proceedings of the National Academy of Sciences · 2016 · 243 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy

Garry Dolton, Cristina Rius, Aaron Wall et al. · Cell · 2023 · 129 citations · Full text

Life Sciences, Immunology, Oncology +17

Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive transfer with tumor-infiltrating lymphocytes in melanoma

Nikolaj Pagh Kristensen, Christina Heeke, Siri Tvingsholm et al. · UCL Discovery (University College London) · 2021 · 109 citations · Full text

Life Sciences, Immunology, Oncology +17

Antibody Stabilization of Peptide–MHC Multimers Reveals Functional T Cells Bearing Extremely Low-Affinity TCRs

Katie Tungatt, Valentina Bianchi, Michael D. Crowther et al. · The Journal of Immunology · 2014 · 57 citations · Full text

Life Sciences, Cell Biology, Immunology +17