Alexandra N. Khristich

RNA–DNA hybrids promote the expansion of Friedreich's ataxia (GAA)n repeats via break-induced replication

Alexander J. Neil, Miranda U Liang, Alexandra N. Khristich et al. · Nucleic Acids Research · 2018 · 82 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Parallel G-quadruplexes formed by guanine-rich microsatellite repeats inhibit human topoisomerase I

Anna Ogloblina, V. A. Bannikova, Alexandra N. Khristich et al. · Biochemistry (Moscow) · 2015 · 56 citations

Life Sciences, Genetics, Molecular Biology +10

Large-scale contractions of Friedreich’s ataxia GAA repeats in yeast occur during DNA replication due to their triplex-forming ability

Alexandra N. Khristich, Jillian F. Armenia, Robert Matera et al. · Proceedings of the National Academy of Sciences · 2020 · 39 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Multi-targeted effects of G4-aptamers and their antiproliferative activity against cancer cells

Anna Ogloblina, Alexandra N. Khristich, Natalia Yu. Karpechenko et al. · Biochimie · 2017 · 27 citations

Medicine, Molecular Biology, Oncology +13

Replication-independent instability of Friedreich’s ataxia GAA repeats during chronological aging

Alexander J. Neil, Julia A. Hisey, Ishtiaque Quasem et al. · Proceedings of the National Academy of Sciences · 2021 · 24 citations · Full text

Medicine, Genetics, Molecular Genetics +17