An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

Steven A. Kliewer, John T. Moore, Laura Wade, +9

Cell

Steroid MetabolismDevelopmental BiologySignal TransductionEndocrine MechanismHormonal Receptor +6

Identification of a nuclear receptor that is activated by farnesol metabolites

Barry M. Forman, Elizabeth C. Goode, Jasmine Chen, +9

Cell

Nuclear ReceptorBiochemistryFunctional SelectivityMedicineNatural Sciences +8

Dopamine Neuron Agenesis in Nurr1-Deficient Mice

Rolf Zetterström, Ludmila Solomin, Lottie Jansson, +2

Science

Docosahexaenoic Acid, a Ligand for the Retinoid X Receptor in Mouse Brain

Alexander Mata de Urquiza, Suya Liu, Maria Sjöberg, +4

Science

Docosahexaenoic AcidBrain DevelopmentSocial SciencesRetinaBrain Maturation +16

Identification of Intrinsic Determinants of Midbrain Dopamine Neurons

Elisabet Andersson, Ulrika Tryggvason, Qiaolin Deng, +5

Cell

Health SciencesNeuroanatomyPhysiologyNeurotransmitterMidbrain Dopamine Neurons +7

Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors

Zhulun Wang, G Benoît, Jinsong Liu, +6

Nature

Signal TransductionG Protein-coupled ReceptorHormonal ReceptorFunctional SelectivityReceptor (Biochemistry) +6

Structural determinants of nuclear receptor assembly on DNA direct repeats

Fraydoon Rastinejad, Thomas Perlmann, Ronald M. Evans, +1

Nature

ChromatinNuclear Receptor AssemblyDnaNatural SciencesGenetics +6

A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1.

Thomas Perlmann, Leif Jansson

Genes & Development

Molecular RegulationNovel PathwayMolecular BiologyAll-trans Retinoic AcidSignaling Pathway +15

Determinants for selective RAR and TR recognition of direct repeat HREs.

Thomas Perlmann, Pundi N. Rangarajan, Kazuhiko Umesono, +1

Genes & Development

Tr RecognitionSelective RarRetinoic AcidMolecular BiologySignal Recognition +15

Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes

Joseph Wagner, Peter Åkerud, Diogo S. Castro, +5

Nature Biotechnology

Type 1NeuroregenerationMidbrain Dopaminergic PhenotypeNeuroanatomyMedicine +9