Rui Tostões

Human liver cell spheroids in extended perfusion bioreactor culture for repeated-dose drug testing

Rui Tostões, Sofia Batista Leite, Margarida Serra et al. · Hepatology · 2011 · 240 citations

Medicine, Biochemistry, Pharmacology +17

Improving expansion of pluripotent human embryonic stem cells in perfused bioreactors through oxygen control

Margarida Serra, Catarina Brito, Marcos F. Q. Sousa et al. · Journal of Biotechnology · 2010 · 149 citations

Engineering, Bioengineering, Cell Biology +16

Extending Hepatocyte Functionality for Drug-Testing Applications Using High-Viscosity Alginate–Encapsulated Three-Dimensional Cultures in Bioreactors

Joana P. Miranda, Armanda Rodrigues, Rui Tostões et al. · Tissue Engineering Part C Methods · 2010 · 101 citations

Engineering, Bioengineering, Biomedical Engineering +17

Perfusion of 3D encapsulated hepatocytes—A synergistic effect enhancing long‐term functionality in bioreactors

Rui Tostões, Sofia Batista Leite, Joana P. Miranda et al. · Biotechnology and Bioengineering · 2010 · 84 citations

Pharmacy, Biochemistry, Drug Delivery +13

Merging bioreactor technology with 3D hepatocyte-fibroblast culturing approaches: Improved in vitro models for toxicological applications

Sofia Batista Leite, Ana P. Teixeira, Joana P. Miranda et al. · Toxicology in Vitro · 2011 · 49 citations

Engineering, Bioengineering, Toxicology +14