Linda Schäker‐Hübner

Synthesis of Peptoid-Based Class I-Selective Histone Deacetylase Inhibitors with Chemosensitizing Properties

Viktoria Krieger, Alexandra Hamacher, Fangyuan Cao et al. · Journal of Medicinal Chemistry · 2019 · 46 citations · Full text

4-Acyl Pyrrole Capped HDAC Inhibitors: A New Scaffold for Hybrid Inhibitors of BET Proteins and Histone Deacetylases as Antileukemia Drug Leads

Linda Schäker‐Hübner, Robin Warstat, Heinz Ahlert et al. · Journal of Medicinal Chemistry · 2021 · 45 citations · Full text

Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase <b>6</b>

Beate König, P. R. Watson, Nina Reßing et al. · Journal of Medicinal Chemistry · 2023 · 41 citations · Full text

Development of the first non-hydroxamate selective HDAC6 degraders

Tim Keuler, Beate König, Nico Bückreiß et al. · Chemical Communications · 2022 · 38 citations

Chromatin, Medicinal Chemistry, Biochemistry +13

Balancing Histone Deacetylase (HDAC) Inhibition and Drug‐likeness: Biological and Physicochemical Evaluation of Class I Selective HDAC Inhibitors

Linda Schäker‐Hübner, Reza Haschemi, Thomas Büch et al. · ChemMedChem · 2022 · 35 citations · Full text