David J. Beech

Piezo1 integration of vascular architecture with physiological force

Jing Li, Bing Hou, Sarka Tumova et al. · Nature · 2014 · 1.2K citations · Full text

Mechanobiology, Engineering, Vascular Adaptation +9

TrpC1 Is a Membrane-Spanning Subunit of Store-Operated Ca ²⁺ Channels in Native Vascular Smooth Muscle Cells

Shang‐Zhong Xu, David J. Beech · Circulation Research · 2001 · 356 citations

Cytoskeleton, Mechanotransduction, Drosophila Trp Gene +20

Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance

Baptiste Rode, Jian Shi, Naima Endesh et al. · Nature Communications · 2017 · 289 citations · Full text

Critical Intracellular Ca2+ Dependence of Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel Activation

Damian McHugh, Richard Flemming, Shang‐Zhong Xu et al. · Journal of Biological Chemistry · 2003 · 287 citations · Full text

TRPC channel activation by extracellular thioredoxin

Shang‐Zhong Xu, Piruthivi Sukumar, Fanning Zeng et al. · Nature · 2008 · 284 citations · Full text

Trpc Channel Activation, Signal Transduction, Molecular Physiology +7