Ieman Aljahdali

Role of Chromatin Damage and Chromatin Trapping of FACT in Mediating the Anticancer Cytotoxicity of DNA-Binding Small-Molecule Drugs

Elimelech Nesher, Alfiya Safina, Ieman Aljahdali et al. · Cancer Research · 2018 · 82 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Tumor p38MAPK signaling enhances breast carcinoma vascularization and growth by promoting expression and deposition of pro-tumorigenic factors

Michelle Limoge, Alfiya Safina, Alexander M. Truskinovsky et al. · Oncotarget · 2017 · 41 citations · Full text

Medicine, Cancer Biology, Oncology +17

FL118, acting as a ‘molecular glue degrader’, binds to, dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c‐Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy

Xiang Ling, Wenjie Wu, Ieman Aljahdali et al. · Clinical and Translational Medicine · 2022 · 38 citations · Full text

Medicine, Molecular Biology, Oncology +13

Mutant Kras as a Biomarker Plays a Favorable Role in FL118-Induced Apoptosis, Reactive Oxygen Species (ROS) Production and Modulation of Survivin, Mcl-1 and XIAP in Human Bladder Cancer

Sreevidya Santha, Xiang Ling, Ieman Aljahdali et al. · Cancers · 2020 · 22 citations · Full text

Medicine, Molecular Biology, Oncology +17