Daniela C. Ifrim

mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

Shih‐Chin Cheng, Jessica Quintin, Robert A. Cramer et al. · Science · 2014 · 2.1K citations · Full text

Microbial Pathogens, Trained Immunity, Innate Immune System +25

Bacille Calmette-Guérin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

Johanneke Kleinnijenhuis, Jessica Quintin, Frank Preijers et al. · Proceedings of the National Academy of Sciences · 2012 · 1.7K citations · Full text

Bcg Vaccination, Microbial Pathogens, Trained Immunity +30

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

Jessica Quintin, Sadia Saeed, Joost H.A. Martens et al. · Cell Host & Microbe · 2012 · 1.2K citations · Full text

Host Response, Pathogenesis, Immunology +7

Trained Immunity or Tolerance: Opposing Functional Programs Induced in Human Monocytes after Engagement of Various Pattern Recognition Receptors

Daniela C. Ifrim, Jessica Quintin, Leo A. B. Joosten et al. · Clinical and Vaccine Immunology · 2014 · 342 citations · Full text

Fungal Chitin Induces Trained Immunity in Human Monocytes during Cross-talk of the Host with Saccharomyces cerevisiae

Lisa Rizzetto, Daniela C. Ifrim, Silvia Moretti et al. · Journal of Biological Chemistry · 2016 · 120 citations · Full text

Dysbiosis, Microbial Pathogens, Tlr Ligands +23