HPGCD Outperforms HPBCD as a Potential Treatment for Niemann-Pick Disease Type C During Disease Modeling with iPS Cells

Minami Soga, Yoichi Ishitsuka, Makoto Hamasaki, +10

Stem Cells

Hpgcd Outperforms HpbcdPathologyTranslational MedicineAutophagyNpc Patients +20

Efficacy of 2-Hydroxypropyl-β-cyclodextrin in Niemann–Pick Disease Type C Model Mice and Its Pharmacokinetic Analysis in a Patient with the Disease

Y. Tanaka, Yusei Yamada, Yoichi Ishitsuka, +14

Biological and Pharmaceutical Bulletin

Subcutaneous InjectionPharmacotherapyPharmacokinetic AnalysisPharmacokineticsPharmacodynamic Modeling +15

The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice

Y. Tanaka, Yoichi Ishitsuka, Marina Hayasaka, +10

Pharmacological Research

InflammationFibrosisAntifibrotic TherapyInflammatory Lung DiseaseBleomycin-induced Pulmonary Fibrosis +9

Effects of intracerebroventricular administration of 2-hydroxypropyl-β-cyclodextrin in a patient with Niemann–Pick Type C disease

Muneaki Matsuo, Koki Shraishi, Koki Wada, +8

Molecular Genetics and Metabolism Reports

Anti-inflammatory Effects of Novel Polysaccharide Sacran Extracted from Cyanobacterium <i>Aphanothece sacrum</i> in Various Inflammatory Animal Models

Keiichi Motoyama, Yuki Tanida, Kyona Hata, +8

Biological and Pharmaceutical Bulletin

Aphanothece SacrumImmunologyAnti-inflammatory EffectsPolysaccharideDermatology +16

Oxidative Stress in Early Stage of Acute Lung Injury Induced with Oleic Acid in Guinea Pigs.

Changqing Yang, Hiroshi Moriuchi, Junko Takase, +3

Biological and Pharmaceutical Bulletin

InflammationAcute Lung InjuryOleic AcidLung InflammationEarly Stage +12

Phosphoenolpyruvic Acid, an Intermediary Metabolite of Glycolysis, as a Potential Cytoprotectant and Anti-oxidant in HeLa Cells

Yuki Kondo, Yoichi Ishitsuka, Daisuke Kadowaki, +9

Biological and Pharmaceutical Bulletin

Lipid PeroxidationSecondary MetaboliteHela CellsRedox BiologyOxidative Stress +20

Preparation of hydrophilic C60(OH)10/2-hydroxypropyl-β-cyclodextrin nanoparticles for the treatment of a liver injury induced by an overdose of acetaminophen

Yoshitaka Umezaki, Daisuke Iohara, Makoto Anraku, +4

Biomaterials

Medicinal ChemistryPharmaceutical Science10/2-Hydroxypropyl-β-cyclodextrin NanoparticlesLiver InjuryCyclodextrin Production +7

Intracerebroventricular Treatment with 2-Hydroxypropyl-β-Cyclodextrin Decreased Cerebellar and Hepatic Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Expression in Niemann–Pick Disease Type C Model Mice

Madoka Fukaura, Yoichi Ishitsuka, Seiichi Shirakawa, +14

International Journal of Molecular Sciences

Evaluation of Three-Dimensional Cultured HepG2 Cells in a Nano Culture Plate System: an In Vitro Human Model of Acetaminophen Hepatotoxicity

Kohei Aritomi, Yoichi Ishitsuka, Yoshiro Tomishima, +6

Journal of Pharmacological Sciences