Jean‐Marc Bielser

Modulation and modeling of monoclonal antibody N‐linked glycosylation in mammalian cell perfusion reactors

Daniel J. Karst, Ernesto Scibona, Elisa Serra et al. · Biotechnology and Bioengineering · 2017 · 92 citations

Improved Performance in Mammalian Cell Perfusion Cultures by Growth Inhibition

Moritz Wolf, Aurélie Closet, Monika Bzowska et al. · Biotechnology Journal · 2018 · 50 citations · Full text

Viable Culture, Engineering, Mammalian Cell Perfusion +21

Perfusion cell culture for the production of conjugated recombinant fusion proteins reduces clipping and quality heterogeneity compared to batch-mode processes

Jean‐Marc Bielser, Loïc Chappuis, Yashi Xiao et al. · Journal of Biotechnology · 2019 · 44 citations

Membrane Fusion, Quality Heterogeneity, Engineering +14

Screening and assessment of performance and molecule quality attributes of industrial cell lines across different fed‐batch systems

Yolande Rouiller, Jean‐Marc Bielser, David Brühlmann et al. · Biotechnology Progress · 2015 · 42 citations

Semi‐continuous scale‐down models for clone and operating parameter screening in perfusion bioreactors

Jean‐Marc Bielser, Jakub Domaradzki, Jonathan Souquet et al. · Biotechnology Progress · 2019 · 37 citations