Guanhua Hou

Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase

Chengqi Yi, Guifang Jia, Guanhua Hou et al. · Nature · 2010 · 143 citations

Iron-catalysed Oxidation Intermediates, Biochemistry, Natural Sciences +7

Stabilization of Different Types of Transition States in a Single Enzyme Active Site: QM/MM Analysis of Enzymes in the Alkaline Phosphatase Superfamily

Guanhua Hou, Qiang Cui · Journal of the American Chemical Society · 2013 · 85 citations · Full text

Transition States, Cellular Enzymology, Biochemistry +14

QM/MM Analysis Suggests That Alkaline Phosphatase (AP) and Nucleotide Pyrophosphatase/Phosphodiesterase Slightly Tighten the Transition State for Phosphate Diester Hydrolysis Relative to Solution: Implication for Catalytic Promiscuity in the AP Superfamily

Guanhua Hou, Qiang Cui · Journal of the American Chemical Society · 2011 · 78 citations

A Modified QM/MM Hamiltonian with the Self-Consistent-Charge Density-Functional-Tight-Binding Theory for Highly Charged QM Regions

Guanhua Hou, Xiao Zhu, Marcus Elstner et al. · Journal of Chemical Theory and Computation · 2012 · 40 citations · Full text

An Implicit Solvent Model for SCC-DFTB with Charge-Dependent Radii

Guanhua Hou, Xiao Zhu, Qiang Cui · Journal of Chemical Theory and Computation · 2010 · 38 citations