Elaine Mai

Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate

Gail D. Lewis Phillips, Guangmin Li, Debra L. Dugger et al. · Cancer Research · 2008 · 1.7K citations

Pharmacy, Oncology, Pharmacology +17

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

Ben‐Quan Shen, Keyang Xu, Luna Liu et al. · Nature Biotechnology · 2012 · 999 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer

Jagath R. Junutula, Kelly M. Flagella, Richard Graham et al. · Clinical Cancer Research · 2010 · 292 citations

Pharmacy, Medicinal Chemistry, Oncology +17

Anti-CD20/CD3 T cell–dependent bispecific antibody for the treatment of B cell malignancies

Liping Sun, Diego Ellerman, Mary Mathieu et al. · Science Translational Medicine · 2015 · 278 citations

Life Sciences, Hematology, Immunology +11

Antibody targeting of E3 ubiquitin ligases for receptor degradation

Hadir Marei, Wen‐Ting K. Tsai, Yee-Seir Kee et al. · Nature · 2022 · 255 citations · Full text

Life Sciences, Biochemistry, Oncology +16