Charles H. Wolstenholme

Modulation of Fluorescent Protein Chromophores To Detect Protein Aggregation with Turn-On Fluorescence

Yu Liu, Charles H. Wolstenholme, Gregory C. Carter et al. · Journal of the American Chemical Society · 2018 · 208 citations · Full text

Engineering, Protein Assembly, Molecular Biology +18

A General Strategy to Control Viscosity Sensitivity of Molecular Rotor‐Based Fluorophores

Songtao Ye, Han Zhang, Jinyu Fei et al. · Angewandte Chemie International Edition · 2020 · 191 citations · Full text

General Strategy, Engineering, Viscosity Sensitivity +22

AggFluor: Fluorogenic Toolbox Enables Direct Visualization of the Multi-Step Protein Aggregation Process in Live Cells

Charles H. Wolstenholme, Hang Hu, Songtao Ye et al. · Journal of the American Chemical Society · 2020 · 144 citations · Full text

Viscosity Sensitivity, Molecular Biology, Cell Proliferation +23

A dual‐functional BODIPY‐based molecular rotor probe reveals different viscosity of protein aggregates in live cells

Baoxing Shen, Kwan Ho Jung, Songtao Ye et al. · Aggregate · 2022 · 62 citations · Full text

Molecular Biology, Peptide Science, Cell Biophysics +18

A General Strategy to Enhance Donor‐Acceptor Molecules Using Solvent‐Excluding Substituents

Conner A. Hoelzel, Hang Hu, Charles H. Wolstenholme et al. · Angewandte Chemie International Edition · 2020 · 57 citations