Mutsuo Oyake

Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique, DIRECT

Kazuhiro Sanpei, Hiroki Takano, S. Igarashi et al. · Nature Genetics · 1996 · 771 citations

Molecular Neuroscience, Direct Identification, Cloning Technique +12

Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

Takayoshi Shimohata, Toshihiro Nakajima, Mitsunori Yamada et al. · Nature Genetics · 2000 · 397 citations

Molecular Physiology, Signal Transduction, Molecular Regulation +9

Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch

Shuichi Igarashi, Reiji Koide, Takayoshi Shimohata et al. · Nature Genetics · 1998 · 357 citations

Polyglutamine Stretch, Drpla Protein, Protein Function +9

Close Associations between Prevalences of Dominantly Inherited Spinocerebellar Ataxias with CAG-Repeat Expansions and Frequencies of Large Normal CAG Alleles in Japanese and Caucasian Populations

Hiroki Takano, Takeshi Ikeuchi, Diego Lorenzetti et al. · The American Journal of Human Genetics · 1998 · 214 citations · Full text

Genetic Disorder, Genetics, Genetic Epidemiology +5

Somatic mosaicism of expanded CAG repeats in brains of patients with dentatorubral-pallidoluysian atrophy: cellular population-dependent dynamics of mitotic instability.

Hiroki Takano, Osamu Onodera, Hitoshi Takahashi et al. · PubMed · 1996 · 86 citations · Full text