Sarah Scott

Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness

Sarah Scott, Paige E. Selvy, Jason R. Buck et al. · Nature Chemical Biology · 2009 · 273 citations · Full text

Medicine, Oncology, Pharmacology +12

FAM83B mediates EGFR- and RAS-driven oncogenic transformation

Rocky Cipriano, James Graham, Kristy Miskimen et al. · Journal of Clinical Investigation · 2012 · 134 citations

Medicine, Cancer Biology, Oncology +17

Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity

Jana A. Lewis, Sarah Scott, Robert R. Lavieri et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 98 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Design, Synthesis, and Biological Evaluation of Halogenated <i>N</i>-(2-(4-Oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: Discovery of an Isoform-Selective Small Molecule Phospholipase D2 Inhibitor

Robert R. Lavieri, Sarah Scott, Paige E. Selvy et al. · Journal of Medicinal Chemistry · 2010 · 90 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease

Fiona E. O’Keeffe, Sarah Scott, Pam Tyers et al. · Brain · 2008 · 86 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17