Hiroyu Hatano

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

Gilad Doitsh, Nicole Galloway, Xin Geng et al. · Nature · 2013 · 1.2K citations · Full text

Life Sciences, Immunology, Infectious Diseases +13

HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality

Sergio Serrano‐Villar, Talía Sainz, Sulggi A. Lee et al. · PLoS Pathogens · 2014 · 614 citations · Full text

Life Sciences, Immunology, Infectious Diseases +16

Antiretroviral Therapy Initiated Within 6 Months of HIV Infection Is Associated With Lower T-Cell Activation and Smaller HIV Reservoir Size

Vivek Jain, Wendy Hartogensis, Peter Bacchetti et al. · The Journal of Infectious Diseases · 2013 · 330 citations · Full text

Life Sciences, Immunology, Adaptive Immunity +15

The Effect of Same-Day Observed Initiation of Antiretroviral Therapy on HIV Viral Load and Treatment Outcomes in a US Public Health Setting

Christopher D. Pilcher, Clarissa Ospina-Norvell, Aditi Dasgupta et al. · JAIDS Journal of Acquired Immune Deficiency Syndromes · 2016 · 256 citations · Full text

Public Health, Pharmacotherapy, Hiv Control +15

Cell-Based Measures of Viral Persistence Are Associated With Immune Activation and Programmed Cell Death Protein 1 (PD-1)–Expressing CD4+ T cells

Hiroyu Hatano, Vivek Jain, Peter W. Hunt et al. · The Journal of Infectious Diseases · 2012 · 255 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17