Exosomes from high glucose-treated glomerular endothelial cells trigger the epithelial-mesenchymal transition and dysfunction of podocytes

Xiaoming Wu, Yanbin Gao, Liping Xu, +9

Scientific Reports

ImmunologyBarrier DysfunctionExtracellular MicrovesiclesCellular PhysiologyEpithelial-mesenchymal Transition +17

Effect of miR-21 on Renal Fibrosis by Regulating MMP-9 and TIMP1 in kk-ay Diabetic Nephropathy Mice

Jinyang Wang, Yanbin Gao, Ming-Fei Ma, +5

Cell Biochemistry and Biophysics

InflammationFibrosisRenal DiseaseAutoimmune DiseaseUrology +12

Emodin mitigates podocytes apoptosis induced by endoplasmic reticulum stress through the inhibition of the PERK pathway in diabetic nephropathy

Nianxiu Tian, Yanbin Gao, Xiaolei Wang, +6

Drug Design Development and Therapy

Astragaloside IV improves renal function and fibrosis via inhibition of miR-21-induced podocyte dedifferentiation and mesangial cell activation in diabetic mice

Xiaolei Wang, Yanbin Gao, Nianxiu Tian, +3

Drug Design Development and Therapy

Astragaloside IV represses high glucose-induced mesangial cells activation by enhancing autophagy via SIRT1 deacetylation of NF-κB P65 subunit

Xiaolei Wang, Yanbin Gao, Nianxiu Tian, +5

Drug Design Development and Therapy

Tongxinluo attenuates atherosclerosis by inhibiting ROS/NLRP3/caspase-1-mediated endothelial cell pyroptosis

Xuejiao Jiang, Chongyang Ma, Yanbin Gao, +5

Journal of Ethnopharmacology

Tangluoning, a traditional Chinese medicine, attenuates in vivo and in vitro diabetic peripheral neuropathy through modulation of PERK/Nrf2 pathway

Xinwei Yang, Weijie Yao, Haolong Liu, +3

Scientific Reports

Tongxinluo ameliorates renal structure and function by regulating miR-21-induced epithelial-to-mesenchymal transition in diabetic nephropathy

Jinyang Wang, Yanbin Gao, Na Zhang, +9

American Journal of Physiology-Renal Physiology

Mir-21 ExpressionRenal PathologyRenal InflammationNephrologyRenal Function +22

Serum miR-21 may be a Potential Diagnostic Biomarker for Diabetic Nephropathy

Juan Wang, Lei Duan, Limin Tian, +4

Experimental and Clinical Endocrinology & Diabetes

Renal PathologyImmunologyRenal InflammationPathologyPotential Diagnostic Biomarker +19

Metformin ameliorates skeletal muscle insulin resistance by inhibiting miR-21 expression in a high-fat dietary rat model

Jinyang Wang, Yanbin Gao, Lijun Duan, +7

Oncotarget

Mir-21 ExpressionInsulin SignalingObesityMetabolic SyndromeMetabolic Signaling +14