Andrew Nichols

An improved trypsin digestion method minimizes digestion-induced modifications on proteins

Da Ren, Gary D. Pipes, Dingjiang Liu et al. · Analytical Biochemistry · 2009 · 190 citations

Protein Chemistry, Protein Secretion, Protein Function +9

Active dimer of Epratuzumab provides insight into the complex nature of an antibody aggregate

Richard L. Remmele, William J. Callahan, Sampathkumar Krishnan et al. · Journal of Pharmaceutical Sciences · 2005 · 61 citations

Allergy, Autoimmune Disease, Immunology +12

Characterization of IgG1 Immunoglobulins and Peptide−Fc Fusion Proteins by Limited Proteolysis in Conjunction with LC−MS

Gerd R. Kleemann, Jill Beierle, Andrew Nichols et al. · Analytical Chemistry · 2008 · 50 citations

Direct Identification and Quantification of Aspartyl Succinimide in an IgG2 mAb by RapiGest Assisted Digestion

Holly Z. Huang, Andrew Nichols, Dingjiang Liu · Analytical Chemistry · 2009 · 43 citations

Gastrointestinal Pharmacology, Glycobiology, Immunology +19

Automated tryptic digestion procedure for HPLC/MS/MS peptide mapping of immunoglobulin gamma antibodies in pharmaceutics

Dirk Chelius, Gang Xiao, Andrew Nichols et al. · Journal of Pharmaceutical and Biomedical Analysis · 2008 · 42 citations

Autoimmune Disease, Bioanalysis, Immunology +9