Patricia A. Brimer

A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): Development and definition of the system

John P. O’Neill, Patricia A. Brimer, Richard Machanoff et al. · Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis · 1977 · 267 citations

Oocyte, Developmental Biology, Quantitative Assay +9

The dose-response relationship for ethyl methanesulfonate-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells

Abraham W. Hsie, Patricia A. Brimer, Toby J. Mitchell et al. · Somatic Cell and Molecular Genetics · 1975 · 193 citations

Biochemistry, Endocrine Mechanism, Medicine +11

A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): Utilization with a variety of mutagenic agents

John P. O’Neill, D.B. Couch, Richard Machanoff et al. · Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis · 1977 · 151 citations

Knockout Mouse, Quantitative Assay, Medicine +9

MAMMALIAN CELL GENETICS I. SELECTION AND CHARACTERIZATION OF MUTATIONS AUXOTROPHIC FOR L-GLUTAMINE OR RESISTANT TO 8-AZAGUANINE IN CHINESE HAMSTER CELLS <i>IN VITRO</i>

E.H.Y. Chu, Patricia A. Brimer, K. Bruce Jacobson et al. · Genetics · 1969 · 146 citations · Full text

Cytogenetics, Iochemical Mutants, Genetics +18

Acrylamide binding to the DNA and protamine of spermiogenic stages in the mouse and its relationship to genetic damage

Gary A. Sega, Ruby P. Valdivia Alcota, Cymbeline P. Tancongco et al. · Mutation Research/Environmental Mutagenesis and Related Subjects · 1989 · 119 citations

Chromatin, Infertility, Genetic Damage +10