Rubén Pavia-Collado

Selective α-Synuclein Knockdown in Monoamine Neurons by Intranasal Oligonucleotide Delivery: Potential Therapy for Parkinson’s Disease

Diana Alarcón-Arís, Ariadna Recasens, Mireia Galofré et al. · Molecular Therapy · 2017 · 131 citations · Full text

Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys

Diana Alarcón-Arís, Rubén Pavia-Collado, Lluís Miquel-Rio et al. · EBioMedicine · 2020 · 73 citations · Full text

Human α-synuclein overexpression in mouse serotonin neurons triggers a depressive-like phenotype. Rescue by oligonucleotide therapy

Lluís Miquel-Rio, Diana Alarcón-Arís, María Torres‐López et al. · Translational Psychiatry · 2022 · 49 citations · Full text

Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mice

Rubén Pavia-Collado, Valentín Cóppola-Segovia, Lluís Miquel-Rio et al. · International Journal of Molecular Sciences · 2021 · 21 citations · Full text

Up and Down γ-Synuclein Transcription in Dopamine Neurons Translates into Changes in Dopamine Neurotransmission and Behavioral Performance in Mice

Rubén Pavia-Collado, Raquel Rodríguez-Aller, Diana Alarcón-Arís et al. · International Journal of Molecular Sciences · 2022 · 11 citations · Full text