Christine C. Vinluan

Secondary Amides of (<i>R</i>)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid as Inhibitors of Pyruvate Dehydrogenase Kinase

Thomas D. Aicher, Robert C. Anderson, Jiaping Gao et al. · Journal of Medicinal Chemistry · 1999 · 68 citations · Full text

Combinatorial Chemistry, Bioorganic Chemistry, Pdhk Inhibitors +16

Anilides of (<i>R</i>)-Trifluoro-2-hydroxy-2-methylpropionic Acid as Inhibitors of Pyruvate Dehydrogenase Kinase

Gregory R. Bebernitz, Thomas D. Aicher, James L. Stanton et al. · Journal of Medicinal Chemistry · 2000 · 60 citations · Full text

Pharmaceutical Science, Oral Bioavailability, Lactate Levels +17

(<i>R</i>)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionamides Are Orally Active Inhibitors of Pyruvate Dehydrogenase Kinase

Thomas D. Aicher, Robert C. Anderson, Gregory R. Bebernitz et al. · Journal of Medicinal Chemistry · 1999 · 43 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Molecular Sciences +14

Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK)

Thomas D. Aicher, Robert E. Damon, Judit Koletar et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 35 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +5

Diverse mechanisms of inhibition of pyruvate dehydrogenase kinase by structurally distinct inhibitors

W. Mann, Carol J. Dragland, Christine C. Vinluan et al. · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · 2000 · 28 citations

Aldehyde Dehydrogenase, Cellular Enzymology, Biochemistry +10