Natalia Slepko

SUMO Modification of Huntingtin and Huntington's Disease Pathology

Joan S. Steffan, Namita Agrawal, Judit Pallos et al. · Science · 2004 · 704 citations · Full text

The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis

Erica Rockabrand, Natalia Slepko, A. Pantalone et al. · Human Molecular Genetics · 2006 · 286 citations · Full text

A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila

Aleksey Kazantsev, Heli A. Walker, Natalia Slepko et al. · Nature Genetics · 2002 · 173 citations

Protein Function, Developmental Biology, Polyglutamine Aggregation +5

A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in <i>Drosophila</i>

Barbara L. Apostol, Alexsey Kazantsev, Simona Raffioni et al. · Proceedings of the National Academy of Sciences · 2003 · 173 citations · Full text

Identification of combinatorial drug regimens for treatment of Huntington's disease using <i>Drosophila</i>

Namita Agrawal, Judit Pallos, Natalia Slepko et al. · Proceedings of the National Academy of Sciences · 2005 · 160 citations · Full text

Molecular Biology, Neurochemical Biomarkers, Optogenetics +17