Ryan M. Friedrich

Modulation of lanosterol synthase drives 24,25-epoxysterol synthesis and oligodendrocyte formation

Zita Hubler, Ryan M. Friedrich, Joel L. Sax et al. · Cell chemical biology · 2021 · 30 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Targeting the chromatin binding of exportin-1 disrupts NFAT and T cell activation

Yifan Chen, Maryam Ghazala, Ryan M. Friedrich et al. · Nature Chemical Biology · 2024 · 20 citations

Life Sciences, Cell Biology, Molecular Biology +16

Inhibition of SC4MOL and HSD17B7 shifts cellular sterol composition and promotes oligodendrocyte formation

M.J. Pleshinger, Ryan M. Friedrich, Zita Hubler et al. · RSC Chemical Biology · 2021 · 16 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Unified Strategy for 1,5,9- and 1,5,7-Triols via Configuration-Encoded 1,5-Polyol Synthesis: Preparation and Coupling of C15–C25 and C26–C40 Fragments of Tetrafibricin

Ryan M. Friedrich, Jay Q. Bell, Alfredo García et al. · The Journal of Organic Chemistry · 2018 · 14 citations

Pharmacy, Chemistry, Medicinal Chemistry +11

C646 degrades Exportin-1 to modulate p300 chromatin occupancy and function

Yifan Chen, Atikur Rahman, Joel L. Sax et al. · Cell chemical biology · 2024 · 14 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +9