Isoprenyl-thiourea and urea derivatives as new farnesyl diphosphate analogues: Synthesis and in vitro antimicrobial and cytotoxic activities

José M. Vega‐Pérez, Ignacio Periñán, Montserrat Argandoña, +7

European Journal of Medicinal Chemistry

Cytotoxic ActivitiesBiochemistryMedicineUrea DerivativesDrug Development +4

GPR120/FFAR4 Pharmacology: Focus on Agonists in Type 2 Diabetes Mellitus Drug Discovery

Gabriele Carullo, Sarah Mazzotta, Margarita Vega‐Holm, +4

Journal of Medicinal Chemistry

Gpr120 AgonistsPharmacotherapyInsulin SignalingMolecular PharmacologyMedicinal Chemistry +14

New 4-Acyl-1-phenylaminocarbonyl-2-phenylpiperazine Derivatives as Potential Inhibitors of Adenovirus Infection. Synthesis, Biological Evaluation, and Structure–activity Relationships

Javier Sánchez‐Céspedes, Pablo Martínez-Aguado, Margarita Vega‐Holm, +6

Journal of Medicinal Chemistry

Antiviral DrugChemical BiologyStructure–activity RelationshipsPharmaceutical ChemistryMedicinal Chemistry +15

New Oleoyl Hybrids of Natural Antioxidants: Synthesis and In Vitro Evaluation as Inducers of Apoptosis in Colorectal Cancer Cells

Gabriele Carullo, Sarah Mazzotta, Adrian Koch, +6

Antioxidants

New Oleoyl HybridsOleic AcidChemoprevention StrategyBiochemistryFood Bioactive Compound +12

Optimization of piperazine-derived ureas privileged structures for effective antiadenovirus agents

Sarah Mazzotta, José Antonio Marrugal‐Lorenzo, Margarita Vega‐Holm, +10

European Journal of Medicinal Chemistry

Bioorganic ChemistryPiperazine-derived UreasNatural SciencesMedicineMolecular Biology +8

New mannose-derived ketones as organocatalysts for enantioselective dioxirane-mediated epoxidation of arylalkenes. Part 3: Chiral ketones from sugars

José M. Vega‐Pérez, Ignacio Periñán, Margarita Vega‐Holm, +2

Tetrahedron

New Mannose-derived KetonesNovel OrganocatalystsEnantioselective SynthesisEnantioselective Dioxirane-mediated EpoxidationEngineering +5

Piperazine-derived small molecules as potential Flaviviridae NS3 protease inhibitors. In vitro antiviral activity evaluation against Zika and Dengue viruses

María del Rosario García-Lozano, Filippo Dragoni, Paloma Gallego, +11

Bioorganic Chemistry

Synthesis of new carbohydrate-derived ketones as organocatalysts in the enantioselective epoxidation of arylalkenes. Part 2: Chiral ketones from sugars

José M. Vega‐Pérez, Margarita Vega‐Holm, Ignacio Periñán, +2

Tetrahedron

Novel OrganocatalystsEnantioselective SynthesisEngineeringOrganic ChemistryNew Carbohydrate-derived Ketones +6

Aziridines from alkenyl-β-D-galactopyranoside derivatives: Stereoselective synthesis and in vitro selective anticancer activity

José M. Vega‐Pérez, Carlos Palo‐Nieto, Margarita Vega‐Holm, +5

European Journal of Medicinal Chemistry

Medicinal ChemistryMedicineDrug DiscoveryStereoselective SynthesisPharmacology +5

Exploration of piperazine-derived thioureas as antibacterial and anti-inflammatory agents. In vitro evaluation against clinical isolates of colistin-resistant Acinetobacter baumannii

Sarah Mazzotta, Tania Cebrero-Cangueiro, Luca Frattaruolo, +9

Bioorganic & Medicinal Chemistry Letters

Antimicrobial Drug DiscoveryAnti-inflammatory AgentsHealth SciencesAntibioticsAntimicrobial Susceptibility +11