Amir Saam Youshani

A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency

Julie Tordo, Claire O’Leary, André Saraiva Leão Marcelo Antunes et al. · Brain · 2018 · 127 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15

Pre-clinical Safety and Efficacy of Lentiviral Vector-Mediated Ex Vivo Stem Cell Gene Therapy for the Treatment of Mucopolysaccharidosis IIIA

Stuart Ellison, Aiyin Liao, Shaun Wood et al. · Molecular Therapy — Methods & Clinical Development · 2019 · 46 citations · Full text

Medicine, Neurology, Neuroscience +17

An Improved Adeno-Associated Virus Vector for Neurological Correction of the Mouse Model of Mucopolysaccharidosis IIIA

Anna L. Gray, Claire O’Leary, Aiyin Liao et al. · Human Gene Therapy · 2019 · 41 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Non-myeloablative busulfan chimeric mouse models are less pro-inflammatory than head-shielded irradiation for studying immune cell interactions in brain tumours

Amir Saam Youshani, Samuel Rowlston, Claire O’Leary et al. · Journal of Neuroinflammation · 2019 · 36 citations · Full text

Life Sciences, Immunology, Oncology +16

A nonmyeloablative chimeric mouse model accurately defines microglia and macrophage contribution in glioma

Kenny Yu, Amir Saam Youshani, Fiona L. Wilkinson et al. · Neuropathology and Applied Neurobiology · 2018 · 22 citations · Full text

Medicine, Immunology, Oncology +13