Bernadett Szikriszt

A comprehensive survey of the mutagenic impact of common cancer cytotoxics

Bernadett Szikriszt, Ádám Póti, Orsolya Pipek et al. · Genome biology · 2016 · 188 citations · Full text

Life Sciences, Genetics, Oncology +17

Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions

Judit Zámborszky, Bernadett Szikriszt, Judit Z. Gervai et al. · Oncogene · 2016 · 149 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents

Ádám Póti, Hella Gyergyák, Eszter Németh et al. · Genome biology · 2019 · 122 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

BRCA1 deficiency specific base substitution mutagenesis is dependent on translesion synthesis and regulated by 53BP1

Dan Chen, Judit Z. Gervai, Ádám Póti et al. · Nature Communications · 2022 · 42 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

A comparative analysis of the mutagenicity of platinum-containing chemotherapeutic agents reveals direct and indirect mutagenic mechanisms

Bernadett Szikriszt, Ádám Póti, Eszter Németh et al. · Mutagenesis · 2021 · 35 citations · Full text

Medicine, Oncology, Toxicology +17