Ya-Li Sang

Sulfonamides containing coumarin moieties selectively and potently inhibit carbonic anhydrases II and IX: Design, synthesis, inhibitory activity and 3D-QSAR analysis

Zhong‐Chang Wang, Yajuan Qin, Pengfei Wang et al. · European Journal of Medicinal Chemistry · 2013 · 63 citations · Full text

Inhibitory Activity, Medicinal Chemistry, Coumarin Moieties +9

Ligand-Based Design of Nondimethylphenyl-Diarylpyrimidines with Improved Metabolic Stability, Safety, and Oral Pharmacokinetic Profiles

Ya-Li Sang, Sheng Han, Christophe Pannecouque et al. · Journal of Medicinal Chemistry · 2019 · 39 citations · Full text

Molecular Hybridization-Inspired Optimization of Diarylbenzopyrimidines as HIV-1 Nonnucleoside Reverse Transcriptase Inhibitors with Improved Activity against K103N and E138K Mutants and Pharmacokinetic Profiles

Sheng Han, Ya-Li Sang, Yan Wu et al. · ACS Infectious Diseases · 2019 · 37 citations · Full text

Conformational restriction design of thiophene-biphenyl-DAPY HIV-1 non-nucleoside reverse transcriptase inhibitors

Ya-Li Sang, Sheng Han, Christophe Pannecouque et al. · European Journal of Medicinal Chemistry · 2019 · 29 citations · Full text

Biochemistry, Natural Sciences, Rational Drug Design +9

Follow on-based optimization of the biphenyl-DAPYs as HIV-1 nonnucleoside reverse transcriptase inhibitors against the wild-type and mutant strains

Ya-Li Sang, Sheng Han, Shuwen Han et al. · Bioorganic Chemistry · 2019 · 27 citations

Engineering, Antiviral Compound, Drug Discovery +12