Rachel L. Clark

Current strategies for drug discovery through natural products

Alan L. Harvey, Rachel L. Clark, Simon P. Mackay et al. · Expert Opinion on Drug Discovery · 2010 · 105 citations

Identification of the benzodiazepines as a new class of antileishmanial agent

Rachel L. Clark, Katharine C. Carter, Alexander B. Mullen et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 48 citations

Medicinal Chemistry, Psychoactive Drug, Antiparasitic Agent +10

Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity

John Spencer, R.P. Rathnam, Alan L. Harvey et al. · Bioorganic & Medicinal Chemistry · 2011 · 38 citations

Medicine, Heterocycle Chemistry, Antitrypanosomal Activity +2

Identification and development of the 1,4-benzodiazepin-2-one and quinazoline-2,4-dione scaffolds as submicromolar inhibitors of HAT

Rachel L. Clark, Carol Clements, Michael P. Barrett et al. · Bioorganic & Medicinal Chemistry · 2012 · 30 citations

Combinatorial Chemistry, Medicinal Chemistry, Quinazoline-2,4-dione Scaffolds +7

Exploring DNA topoisomerase I inhibition by the benzo[c]phenanthridines fagaronine and ethoxidine using steered molecular dynamics

Rachel L. Clark, Fiona M. Deane, Nahoum G. Anthony et al. · Bioorganic & Medicinal Chemistry · 2007 · 16 citations

Medicinal Chemistry, Pharmaceutical Chemistry, Bioorganic Chemistry +10