Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis

Roberto Carlos Agís‐Balboa, Graziano Pinna, Adrian Zhubi, +4

Proceedings of the National Academy of Sciences

Brain NeuronsCerebral OrganoidSocial SciencesNeurogenesisNeurochemistry +17

In psychosis, cortical interneurons overexpress DNA-methyltransferase 1

Marin Veldić, Alessandro Guidotti, Ekrem Maloku, +2

Proceedings of the National Academy of Sciences

The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases

Maria Vittoria Simonini, Luiz Miguel Camargo, Erbo Dong, +4

Proceedings of the National Academy of Sciences

Histone ModificationsHistone DeacetylasesEpigenetic ChangePsychopharmacologyEpigenetics +16

Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons

Rosalba Satta, Ekrem Maloku, Adrian Zhubi, +4

Proceedings of the National Academy of Sciences

Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder

Marin Veldić, Bashkim Kadriu, Ekrem Maloku, +4

Schizophrenia Research

PsychiatryGeneticsSchizophreniaNeuropsychiatryEpigenetic Mechanisms +8

Lower number of cerebellar Purkinje neurons in psychosis is associated with reduced reelin expression

Ekrem Maloku, Ignacio R. Covelo, Ingeborg Hanbauer, +5

Proceedings of the National Academy of Sciences

GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability

Erminio Costa, Ying Chen, Erbo Dong, +8

Expert Review of Neurotherapeutics

NeuropsychologyPsychopharmacologyNeuropsychiatrySchizophrenia VulnerabilityEpigenetics +19

Selective α4β2 Nicotinic Acetylcholine Receptor Agonists Target Epigenetic Mechanisms in Cortical GABAergic Neurons

Ekrem Maloku, Bashkim Kadriu, Adrian Zhubi, +4

Neuropsychopharmacology

Synaptic SignalingNeurotransmitterNeuropharmacologyNeurotransmissionNeurology +5

Clinical utility of whole-genome DNA methylation profiling as a primary molecular diagnostic assay for central nervous system tumors—A prospective study and guidelines for clinical testing

Kristyn Galbraith, Varshini Vasudevaraja, Jonathan Serrano, +58

Neuro-Oncology Advances

Phase 0 Clinical Trial of Everolimus in Patients with Vestibular Schwannoma or Meningioma

Matthias A. Karajannis, Audrey Mauguen, Ekrem Maloku, +19

Molecular Cancer Therapeutics