Javier Vargas‐Medrano

FTY720/Fingolimod Reduces Synucleinopathy and Improves Gut Motility in A53T Mice

Guadalupe Vidal-Martínez, Javier Vargas‐Medrano, Carolina Gil-Tommee et al. · Journal of Biological Chemistry · 2016 · 70 citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Disease Mechanism +7

FTY720 Improves Behavior, Increases Brain Derived Neurotrophic Factor Levels and Reduces α-Synuclein Pathology in Parkinsonian GM2 +/− Mice

Guadalupe Vidal-Martínez, Katherine Najera, Julie D. Miranda et al. · Neuroscience · 2019 · 38 citations · Full text

Novel FTY720-Based Compounds Stimulate Neurotrophin Expression and Phosphatase Activity in Dopaminergic Cells

Javier Vargas‐Medrano, Sesha Krishnamachari, Ernesto Villanueva et al. · ACS Medicinal Chemistry Letters · 2014 · 35 citations

Dopaminergic Cells, Degenerative Pathology, Neurology +16

FTY720 (Fingolimod) reverses α-synuclein-induced downregulation of brain-derived neurotrophic factor mRNA in OLN-93 oligodendroglial cells

Ismael Segura‐Ulate, Barbara Yang, Javier Vargas‐Medrano et al. · Neuropharmacology · 2017 · 34 citations · Full text

Synaptic Plasticity, Neurodegenerative Diseases, Molecular Neuroscience +14

Altered levels of interleukins and neurotrophic growth factors in mood disorders and suicidality: an analysis from periphery to central nervous system

Bharathi S. Gadad, Javier Vargas‐Medrano, Enrique Ramos et al. · Translational Psychiatry · 2021 · 33 citations · Full text