Didier Scherrer

Long lasting control of viral rebound with a new drug ABX464 targeting Rev – mediated viral RNA biogenesis

Noëlie Campos, Renier Myburgh, Aude Garcel et al. · Retrovirology · 2015 · 96 citations · Full text

RabGEF1 is a negative regulator of mast cell activation and skin inflammation

See‐Ying Tam, Mindy Tsai, John N. Snouwaert et al. · Nature Immunology · 2004 · 62 citations

Inflammation, Cytokine, Signal Transduction +13

Both anti-inflammatory and antiviral properties of novel drug candidate ABX464 are mediated by modulation of RNA splicing

Audrey Vautrin, Laurent Manchon, Aude Garcel et al. · Scientific Reports · 2019 · 62 citations · Full text

Interleukin-1beta induces bradykinin B2 receptor gene expression through a prostanoid cyclic AMP-dependent pathway in human bronchial smooth muscle cells.

Fabien Schmidlin, Didier Scherrer, Laurent Daeffler et al. · PubMed · 1998 · 59 citations

Inflammation, Cytokine, Interleukin-1beta Induces +15

ABX464 (obefazimod) for moderate-to-severe, active ulcerative colitis: a phase 2b, double-blind, randomised, placebo-controlled induction trial and 48 week, open-label extension

Séverine Vermeire, Bruce E. Sands, Herbert Tilg et al. · ˜The œLancet. Gastroenterology & hepatology · 2022 · 58 citations

Inflammation, Gastrointestinal Pharmacology, Phase 2B +6