Cassette dosing: rapid in vivo assessment of pharmacokinetics

Lloyd Frick, Kimberly K. Adkison, Kevin J. Wells‐Knecht, +2

Pharmaceutical Science & Technology Today

Cassette DosingPharmacologyPharmacotherapyMedicinePhysiologically-based Pharmacokinetic Modeling +1

European Bioanalysis Forum Recommendation: Scientific Validation of Quantification by Accelerator Mass Spectrometry

David Higton, Graeme Young, Philip Timmerman, +3

Bioanalysis

Scientific ValidationSpectrochemical AnalysisAnalytical InstrumentationBioanalysisBiostatistics +16

An investigation into the application of capillary electrochromatography-mass spectrometry (CEC-MS) for the analysis and quantification of a potential drug candidate in extracted plasma

Clare J. Paterson, Robert J. Boughtflower, David Higton, +1

Chromatographia

Extracted PlasmaGas ChromatographyDrug PurityBioanalysisAnalytical Chemistry +14

Determination of 4‐hydroxytamoxifen in mouse plasma in the pg/mL range by gradient capillary liquid chromatography/tandem mass spectrometry

Robert S. Plumb, H. Warwick, David Higton, +2

Rapid Communications in Mass Spectrometry

BiochemistryMedicineBioanalysisMass SpectrometryPg/ml Range +12

A structure–activity relationship linking non-planar PCBs to functional deficits of neural crest cells: new roles for connexins

Johanna Nyffeler, Petra Chovancova, Xenia Dolde, +12

Archives of Toxicology

The potential of serially coupled alkyl-bonded silica monolithic columns for high resolution separations of pharmaceutical compounds in biological fluids

Gordon J. Dear, David N. Mallett, David Higton, +5

Chromatographia

Biological FluidsEngineeringSeparation ScienceMedicineSelective Separation +11

Ask The Experts: Automation: Part I

John Allinson, Kenneth E. Blick, Lucinda H. Cohen, +2

Bioanalysis

Artificial IntelligenceEngineeringIntelligent SystemsBiomedical EngineeringProcess Automation +15

Use of Cyclic Ion Mobility Spectrometry (cIM)-Mass Spectrometry to Study the Intramolecular Transacylation of Diclofenac Acyl Glucuronide

David Higton, Martin Palmer, Johannes P.C. Vissers, +3

Analytical Chemistry

Absorption and disposition of ranitidine hydrochloride in rat and dog

Peter Eddershaw, Aa.P Chadwick, David Higton, +5

Xenobiotica

Animal PhysiologyDose LevelPharmacokinetic ModelingPharmacological StudyRanitidine Hydrochloride +11

Investigation into Small Molecule Isomeric Glucuronide Metabolite Differentiation Using <i>In Silico</i> and Experimental Collision Cross-Section Values

John R. F. B. Connolly, J. A. Muñoz, Cris Lapthorn, +5

Journal of the American Society for Mass Spectrometry