Senliang Pan

A Strategy to Minimize Reactive Metabolite Formation: Discovery of (<i>S</i>)-4-(1-Cyclopropyl-2-methoxyethyl)-6-[6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino]-5-oxo-4,5-dihydropyrazine-2-carbonitrile as a Potent, Orally Bioavailable Corticotropin-Releasing Factor-1 Receptor Antagonist

Richard A. Hartz, Vijay T. Ahuja, Xiaoliang Zhuo et al. · Journal of Medicinal Chemistry · 2009 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure–Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H ₁ Receptor Inverse Agonist

Manjinder S. Lall, Asser Bassyouni, James Bradow et al. · Journal of Medicinal Chemistry · 2020 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of hIV-1 non-nucleoside reverse transcriptase

Jeffrey W. Corbett, Kristen Jill Kresge, Senliang Pan et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 17 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

3,3a-Dihydropyrano[4,3,2-de]quinazolin-2(1H)-ones are potent non-nucleoside reverse transcriptase inhibitors

Jeffrey W. Corbett, Senliang Pan, Jay A. Markwalder et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 16 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +6