James G. Karras

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

Guilian Niu, Kenneth L. Wright, Mei Huang et al. · Oncogene · 2002 · 1.2K citations

Angiogenesis, Cancer Growth, Vascular Biology +5

Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

Pearlie K. Epling‐Burnette, Jin Hong Liu, Robyn Catlett-Falcone et al. · Journal of Clinical Investigation · 2001 · 642 citations · Full text

Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells.

Linda Mora, Ralf Buettner, John D. Seigne et al. · PubMed · 2002 · 536 citations

Apoptosis, Immunology, Cell Death +18

Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target

Roberto Chiarle, William J. Simmons, Honjying Cai et al. · Nature Medicine · 2005 · 434 citations

Lymphoid Neoplasia, Alk-mediated Lymphomagenesis, Possible Therapeutic Target +8

Role of Stat3 in Regulating p53 Expression and Function

Guilian Niu, Kenneth L. Wright, Yihong Ma et al. · Molecular and Cellular Biology · 2005 · 395 citations · Full text

Cancer Research, Signaling Pathway, Cell Regulation +12