Activation of Hypoxia-Inducible Factors Prevents Diabetic Nephropathy

Lina Nordquist, Malou Friederich‐Persson, Angelica Fasching, +5

Journal of the American Society of Nephrology

Redox SignalingMetabolic SyndromeHypoxia-inducible FactorsBiochemistryTissue Hypoxia +13

Painless Drug Delivery Through Microneedle-Based Transdermal Patches Featuring Active Infusion

Niclas Roxhed, Björn Samel, Lina Nordquist, +2

IEEE Transactions on Biomedical Engineering

NanomedicineEngineeringDelivery SystemBioelectronicsTopical Drug +9

Novel Microneedle Patches for Active Insulin Delivery are Efficient in Maintaining Glycaemic Control: An Initial Comparison with Subcutaneous Administration

Lina Nordquist, Niclas Roxhed, Patrick Griss, +1

Pharmaceutical Research

Diabetes ManagementInsulin ManagementDiabetesActive Insulin DeliveryNovel Microneedle Patches +4

Diabetes-induced up-regulation of uncoupling protein-2 results in increased mitochondrial uncoupling in kidney proximal tubular cells

Malou Friederich, Angelica Fasching, Peter Hansell, +2

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Metabolic SyndromeMitochondrial FunctionDiabetes-induced Up-regulationMedicinePhysiology +12

Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress

Fredrik Palm, Masaomi Nangaku, Angelica Fasching, +6

American Journal of Physiology-Renal Physiology

Renal PathologyRenal InflammationOxygen MetabolismRedox BiologyOxidative Stress +16

Trafficking of ENaC subunits in response to acute insulin in mouse kidney

Swasti Tiwari, Lina Nordquist, Veerendra K. Madala Halagappa, +1

American Journal of Physiology-Renal Physiology

Proinsulin C-peptide reduces diabetes-induced glomerular hyperfiltration via efferent arteriole dilation and inhibition of tubular sodium reabsorption

Lina Nordquist, Russell D. Brown, Angelica Fasching, +2

American Journal of Physiology-Renal Physiology

Tubular Sodium ReabsorptionRenal FunctionNet DilationMedicineChronic Kidney Disease +12

Acute Knockdown of Uncoupling Protein-2 Increases Uncoupling via the Adenine Nucleotide Transporter and Decreases Oxidative Stress in Diabetic Kidneys

Malou Friederich‐Persson, Shakil Aslam, Lina Nordquist, +3

PLoS ONE

Proinsulin C-peptide constricts glomerular afferent arterioles in diabetic mice. A potential renoprotective mechanism

Lina Nordquist, En Yin Lai, Mats Sjöquist, +2

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

The C‐peptide fragment EVARQ reduces glomerular hyperfiltration in streptozotocin‐induced diabetic rats

Lina Nordquist, Erika Moe, Mats Sjöquist

Diabetes/Metabolism Research and Reviews